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Kaufen Probalan Online

  • €0,74
  • Verfügbarkeit: Lagernd
  • Wirkstoff: Probenecid
Probalan (Probenecid) wird zur Behandlung von chronischer oder arthritischer Gicht verwendet.
Analog zu Probalan: Benemid  
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500 mg
Produktname Pro Pille Pro Packung  
30 pillen €1,15 €34,36
60 pillen €0,93 €68,72 €55,60
90 pillen €0,85 €103,09 €76,84
120 pillen €0,82 €137,45 €98,09
180 pillen €0,78 €206,17 €140,57
270 pillen €0,76 €309,26 €204,29
360 pillen €0,74 €412,34 €268,02

INDICATIONS

Probalan is used in the treatment of chronic gout or gouty arthritis. These conditions are caused by too much uric acid in the blood.

INSTRUCTIONS 

Use Probalan as directed by your doctor.

Take Probalan tablets by mouth.
Swallow the tablets with a drink of water.
Take your doses at regular intervals.

If you miss a dose of Probalan, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Probalan.

STORAGE

Store Probalan at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Probalan out of the reach of children and away from pets.

MORE INFO:

Active Ingredient: Probenecid

Probalan works by removing the extra uric acid from the body. Probalan does not cure gout, but after you have been taking it for a few months it will help prevent gout attacks. Probalan will help prevent gout attacks only as long as you continue to take it.

Probalan is also used to prevent or treat other medical problems that may occur if too much uric acid is present in the body.

Probalan is sometimes used with certain kinds of antibiotics to make them more effective in the treatment of infections.

SAFETY INFORMATION

Do not use Probalan if:

you are allergic to any ingredient in Probalan;

you have blood problems or kidney stones caused by uric acid;
the patient is a child younger than 2 years of age;

you are taking salicylates (e.g., aspirin).

Contact your doctor or health care provider right away if any of these apply to you.

Important information: 

Do not use Probalan if:

 

you are allergic to any ingredient in Probalan;

 

you have blood problems or kidney stones caused by uric acid;
the patient is a child younger than 2 years of age;

 

you are taking salicylates (e.g., aspirin).

Contact your doctor or health care provider right away if any of these apply to you.


Important information:

Probalan may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Probalan. Using Probalan alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks. 

Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Probalan. 
Diabetes patients - Probalan may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
Probalan may interfere with some lab tests (e.g., blood or hemoglobin urine tests, theophylline levels). Make sure your doctor and lab personnel know you are using Probalan.
Lab tests, including tests for sugar in the urine, may be required to monitor your progress. Be sure to keep all doctor and lab appointments.
Use of Probalan is not recommended in children younger than 2 years of age. Safety and effectiveness in this age group have not been confirmed.

Pregnancy and breast-feeding: If you become pregnant while taking Probalan, discuss with your doctor the benefits and risks of using Probalan during pregnancy. Probalan is excreted in breast milk. If you are or will be breast-feeding while you are using Probalan, check with your doctor or pharmacist to discuss the risks to your baby.

SIDE EFFECTS

Check with your doctor if any of these most common side effects persist or become bothersome:

dizziness; flushing; hair loss; headache; loss of appetite; nausea; sore gums; vomiting.

Seek medical attention right away if any of these severe side effects occur:

severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in the urine; chills; dark urine; decreased or increased urination; fever; lower back, lower stomach, genital, or inner thigh pain; persistent sore throat; severe or persistent nausea, vomiting, or stomach pain; unusual bleeding or bruising; unusual tiredness or weakness; worsening gout; yellowing of the eyes or skin.

More Information

Probalan is to be used only by the patient for whom it is prescribed. Do not share it with other people. 
If your symptoms do not improve or if they become worse, check with your doctor.

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Rare

  • Fast or irregular breathing
  • puffiness or swellings of the eyelids or around the eyes
  • shortness of breath, troubled breathing, tightness in chest, or wheezing
  • changes in the skin color of the face occurring together with any of the other side effects listed here
  • or skin rash, hives, or itching occurring together with any of the other side effects listed here
  • Cloudy urine
  • cough or hoarseness
  • fast or irregular breathing
  • fever
  • pain in back and/or ribs
  • sores, ulcers, or white spots on lips or in mouth
  • sore throat and fever with or without chills
  • sudden decrease in the amount of urine
  • swelling of face, fingers, feet, and/or lower legs
  • swollen and/or painful glands
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • yellow eyes or skin
  • weight gain

More Common

  • Headache
  • joint pain, redness, or swelling
  • loss of appetite
  • nausea or vomiting (mild)

Less Common

  • Bloody urine
  • difficult or painful urination
  • lower back or side pain (especially if severe or sharp)
  • skin rash, hives, or itching (occurring without other signs of an allergic reaction)
  • Dizziness
  • flushing or redness of face (occurring without any signs of an allergic reaction)
  • frequent urge to urinate
  • sore gums
Type Small Molecule
Accession Number DB01032  (APRD00167)
Groups Approved, Investigational
Synonyms
  • 4-((Dipropylamino)sulfonyl)benzoic acid
  • 4-(Di-N-propylsulfamoyl)benzoesaeure
  • 4-(N,N-Dipropylsulfamoyl)benzoesaeure
  • P-(Dipropylsulfamoyl)benzoic acid
  • Probenecid acid
  • Probenecida
  • Probenecide
  • Probenecidum
UNII PO572Z7917
CAS number 57-66-9
Weight Average: 285.359
Monoisotopic: 285.103478791
Chemical Formula C13H19NO4S
InChI
InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16)
IUPAC Name
4-(dipropylsulfamoyl)benzoic acid
Protein binding

75-95%

Toxicity Not Available
Half life

6-12 hours

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